Ionis Pharmaceuticals, Inc. (NASDAQ:IONS)

Isis Pharmaceuticals, Inc. (Isis), incorporated in January 10, 1989, is engaged in antisense technology, exploiting a drug discovery platform to create a pipeline of drugs. As of December 31, 2011, the Company operates in the Drug Discovery and Development operations segments. The Drug Discovery and Development operations help the Company to identify drugs, providing a wealth of potential targets to treat a range of diseases. As of December 31, 2011, the Company had two generation 2.5 drugs in development, ISIS-STAT3Rx and ISIS-FVIIRx. During the year ended December 31, 2011, the Company had 26 drugs in development. Its partners are licensed to develop, with the Company’s support, 10 of these 26 drugs. As of December 31, 2011, the Company owns 20% interests in Santaris Pharma A/S, Achaogen Inc., and Atlantic Pharmaceuticals Limited, which are privately-held, and Antisense Therapeutics Limitet (ATL), and iCo Therapeutics Inc., which are publicly utilities.